Breast Cancer Cell Lines Subtypes
Gene expression profiles of 51 human breast cancer cell lines. Application of sophisticated transcriptional profiling to breast cancer cell lines using various platforms has gone some way to address these issues.
Molecular Profiling Of Breast Cancer Cell Lines Defines Relevant
The comprehensive breast cancer cell panel atcc no 30 4500k is a comprehensive set of 45 breast cancer cell lines derived from atcc master seed stocks.
Breast cancer cell lines subtypes. Ductal carcinoma is the most common type of breast cancer. Genes were restricted to those showing significant variance across all samples resulting in clustering of 1438 probe sets see experimental procedures. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes.
Recent studies suggest that thousands of genes may contribute to breast cancer pathophysiologies when deregulated by genomic or epigenomic events. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes author links open overlay panel richard m. Hierarchical cluster analysis of breast cancer cell lines with subclusters i through v indicated by colored bars at side.
In general these studies have shown that the luminal basal her2 and claudin low clusters identified in breast tumours can easily be distinguished in breast cancer cell lines table 1 13 22. Each panel features a cd containing signed certificates of analyses and product sheets for each individual cell line. Neve 1 2 9 koei chin 2 9 jane fridlyand 2 6 jennifer yeh 2 frederick l.
Authors richard m neve 1. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Parts of the breast where cancer begins include.
Distinct gene mutation profiles among luminal type and basal type breast cancer cell lines. Spellman 1 sandy devries 2. Cell line primary tumor origin of cells estrogen receptors progesterone receptors erbb2 amplification mutated tp53 tumorigenic in mice reference external links.
List of cell lines. Breast cancer research and treatment. The type of tissue where your breast cancer arises determines how the cancer behaves and what treatments are most effective.
Hollestelle a nagel jh smid m lam s elstrodt f wasielewski m. Here we describe a model system to appraise the functional contributions of these genes to breast cancer subsets. Neve rm 1 chin k fridlyand j yeh j baehner fl fevr t clark l bayani n coppe jp tong f speed t spellman pt devries s lapuk a wang nj kuo wl stilwell jl pinkel d albertson dg waldman fm mccormick f dickson rb johnson md lippman.
Baehner 2 tea fevr 2 laura clark 1 nora bayani 1 jean philippe coppe 1 frances tong 3 terry speed 3 paul t. In general the recurrent genomic and transcriptional characteristics of 51 breast cancer cell lines mirror those of 145 primary. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes cancer cell.
This is a list of major breast cancer cell lines that are primarily used in breast cancer research. This type of cancer forms in the lining of a milk duct within your breast.
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Subtype Of The Breast Cancer Cell Lines Used In The Experiments
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