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It is used in rheumatoid arthritis granulomatosis with polyangiitis crohn s disease ulcerative colitis systemic lupus erythematosus and in kidney transplants to prevent rejection. One metabolic pathway is through its conversion to 6 mercaptopurine the active metabolite of 6 mercaptopurine being 6 …

Inhibition of the cell cycle azathioprine cyclophosphamide methotrexate and mycophenolate mofetil. Azathioprine also may integrate into nucleic acids resulting in chromosome breakage nucleic acid malfunction or the synthesis of faulty proteins. Myasthenia Gravis Neurology Internal Medicine Corre…